Bionized NanoFerrite particles (BNF-Dextran and BNF-Starch)

  • are prepared via the core-shell method with a core of 75-80% (w/w) magnetite and a shell of dextran or hydroxyethyl starch,

  • are available with particle diameters of 80 nm and 100 nm,

  • are thermally blocked at room temperature and show specific interaction with alternating magnetic fields (Dennis et al. 2008 und 2009; Krycka et al., 2011; Bordelon et al., 2011),

  • 100 nm particles can be separated with conventional permanent magnets,

  • 80 nm particles have to be separated in high gradient magnetic fields,

  • are designed with the surface functionalities OH (plain), NH2, PEG-NH2, COOH, PEG-COOH and maleimide for the covalent binding of proteins, antibodies or other molecules,

  • are available with covalently bound proteins (streptavidin, protein A),

  • can be provided with covalently bound antibodies on request,

  • can easily be filtered through 0.22 µm filters.